Background & Aims: Cirrhosis from hepatitis C
virus (HCV) infection is a major cause of end-stage liver disease and
hepatocellular carcinoma worldwide. We determine the prevalence of
cirrhosis among HCV-infected American adults including those unaware of
their infection.
Methods: Using the National Health and Nutrition Examination Survey (NHANES) data, we identified participants aged P20 years with detectable serum HCV RNA. The prevalence of advanced fibrosis and cirrhosis was determined for eras 1 (1988–94), 2 (1999–2006) and 3 (2007–2012) by using FIB-4 3.25 and APRI 2.0, respectively.
Results: Out of 52,644 NHANES examinees, 49,429 were tested for
Methods: Using the National Health and Nutrition Examination Survey (NHANES) data, we identified participants aged P20 years with detectable serum HCV RNA. The prevalence of advanced fibrosis and cirrhosis was determined for eras 1 (1988–94), 2 (1999–2006) and 3 (2007–2012) by using FIB-4 3.25 and APRI 2.0, respectively.
Results: Out of 52,644 NHANES examinees, 49,429 were tested for
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